Publications

Publications by Prof. Dr. Jörg Wilting

2015

Wilting, J., Männer, J.: Vascular Embryology. In: Vascular Malformations and Hemangiomas: An Atlas of Diagnosis and Treatment, 2nd Edition. Springer, Mailand, Italy (2015, in press)

Buttler, K., Wilting, J.: Biomarkers. In: Lymphedema. Quality Medical Publishing, Inc., CRC Press, Abingdon, UK (2015, in press)

Mattonet, K., Wilting, J., Jeltsch, M.: Die genetischen Ursachen des primären Lymphödems. In: Erkrankungen des Lymphgefäßsystems, 6. Aufl., (eds. Weissleder H, Schuchhardt C), Viavital Verlag, Köln, (2015, in press)

Wilting, J., Chao, T.I.: Integrated anatomy of the vascular system. In: Panvascular Medicine (ed. Lanzer, P.) 2nd Edition, Vol. 1, Springer Verlag, Heidelberg, New York, Dordrecht, London (2015) pp 193 – 242

2014

Buttler, K., Badar, M., Seiffart, V., Laggies, S., Gross, G., Wilting, J., Weich, H.A.: De novo hem- and lymphangiogenesis by endothelial progenitor and mesenchymal stem cells in immunocompetent mice. Cell. Mol. Life Sci. 71: 1513-1527 (2014)
Deutsche Version: Buttler, K., Gross, G., Wilting, J., Weich, H.A.: Induktion von Blut- und Lymphgefäßen durch endotheliale Progenitorzellen und mesenchymale Stammzellen in der Maus. Lymphologie in Forschung und Praxis 18: 72-77 (2014)

Klingenberg, M., Becker, J., Eberth, S., Kube, D., Wilting, J.: The NADPH oxidase inhibitor imipramine-blue in the treatment of Burkitt lymphoma. Mol. Cancer Ther. 13: 833-841 (2014)

Klingenberg, M., Becker, J., Kube, D., Wilting J.: The chick chorioallantoic membrane as an in vivo xenograft model for Burkitt lymphoma. BMC Cancer 14: 339 (2014)

Alwahsh, S.M., Xu, M., Schultze, F.C., Wilting, J., Mihm, S., Raddatz, D., Ramadori, G.: Combination of alcohol and fructose exacerbates metabolic imbalance in terms of hepatic damage, dyslipidemia, and insulin resistance in rats. Plos One 9(8): e104220 (2014)

Bartowski, R., Bauernfeind, G., Becher, K., Bunse, J., Burckhardt, M., Buß, A., Feuerer, H., Freier, F.J., Goedecke, F., Gregor, S., Hadamitzky, C.D., Hirsch, T., Kleijnen, J., Klug, E., Hack, A., Maier-Hasselmann, A., Meyer, G., Mirastschijski, U., Niederbichler, A.D., Nink-Grebe, B., Pschicholz, R., Rüttermann, M., Seipp, H.-M., Sorg, H., Strupeit, S., Stiegler, H., Vogt, P., Waldvogel-Röcker, K., Weberschock, T., Welslau, W., Wilting, J., Wilm, S., Wolff, R.: Kurzfassung S3-Leitlinie: Lokaltherapie chronischer Wunden bei Patienten mit den Risiken periphere arterielle Verschlusskrankheit, Diabetes mellitus, chronisch venöse Insuffizienz. Zeitschrift für Wundheilung 19: 1-31 (2014)

Wilting, J.: Genetische Ursachen des primären Lymphödems. Lymphologie in Forschung und Praxis 18: 26-30 (2014)
Republiziert: Wilting, J.: Genetische Ursachen des primären Lymphödems. Vasomed 26: 313-317 (2014)

Buttler, K., Kasten, P., Wilting, J.: Genese und Pathogenese des Lymphgefäßsystems. In: Teratologie heute. (eds. Fanghänel J., Behr M., Proff P.) Kiebudruck, Greifswald 2014, pp 123-127

2013

Buttler, K., Becker, J., Pukrop, T., Wilting, J.: Maldevelopment of dermal lymphatics in Wnt5a-knock-out mice. Dev Biol 381: 365-376 (2013)

Deutsche Version: Buttler, K., Pukrop, T., Becker, J., Wilting, J.: Regulation dermaler Lymphgefäße durch das Entwicklungskontrollgen WNT5A. Lymphologie in Forschung und Praxis 17: 62-69 (2013)

Exertier, P., Javerzat, S., Wang, B., Franco, M., Herbert, J., Platonova, N., Winandy, M., Nivelles, O., Ormenese, S., Godard, V., Becker, J., Bicknell, R., Cherifi, K., Wilting, J., Bikfalvi, A., Hagedorn, M.: Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5. Oncotarget 4: 2302-2316 (2013)

Wilting, J., Männer, J.: Development and Patterning of the Cardiac Lymphatic Network. In: The Cardiac Lyphatic System: An Overview (ed. Karunamuni G), Springer, New York, NY, 2013, pp 17-31

2012

Becker, J., Fröhlich, J., Hansen, J., Zelent, C., Perske, C., Wilting, J.: The lymphangiogenesis inhibitor esVEGFR-2 in human embryos: expression in sympatho-adrenal tissues and differentiation-induced up-regulation in neuroblastoma. Histol Histopathol 27: 721-733 (2012)

Becker, J., Covelo-Fernandez, A., von Bonin, F., Kube, D., Wilting, J.: Specific tumor-stroma interactions of EBV-positive Burkitt's lymphoma cells in the chick chorioallantoic membrane. Vascular Cell 4: 3 (2012)

Becker, J., Fröhlich, J., Perske, C., Pavlakovic, H., Wilting, J.: Reelin signalling in neuroblastoma: migratory switch in metastatic stages. Int. J. Oncol. 41: 681-689 (2012)

Bartowski, R., Bauernfeind, G., Becher, K., Bunse, J., Burckhardt, M., Buß, A., Feuerer, H., Freier, F.J., Goedecke, F., Gregor, S., Hadamitzky, C.D., Hirsch, T., Kleijnen, J., Klug, E., Hack, A., Maier-Hasselmann, A., Meyer, G., Mirastschijski, U., Niederbichler, A.D., Nink-Grebe, B., Pschicholz, R., Rüttermann, M., Seipp, H.-M., Sorg, H., Strupeit, S., Stiegler, H., Vogt, P., Waldvogel-Röcker, K., Weberschock, T., Welslau, W., Wilting, J., Wilm, S., Wolff, R. (2012) Lokaltherapie chronischer Wunden bei Patienten mit den Risiken periphere arterielle Verschlusskrankheit, Diabetes mellitus, chronisch venöse Insuffizienz. AWMF online; http://www.awmf.org/leitlinien/detail/ll/091-001.html

2011

Hemmen, K., Reinl, T., Buttler, K., Behler, F., Dieken, H., Jaensch, L., Wilting, J., Weich,H.A.: High-resolution mass spectrometric analysis of the secretome from mouse lung endothelial progenitor cells. Angiogenesis 14: 163-172 (2011)

Buttler, K., Wilting, J.: Das Lymphgefäßsystem bei der Entzündung: Ein wenig beachtetes Forschungsgebiet. Lymphologie in Forschung und Praxis 15: 2-8 (2011)

Wilting, J., Hagedorn, M.: Left-right asymmetry in embryonic development and breast cancer: common molecular determinants? Curr. Med. Chem. 18: 5519-5527 (2011)

2010

Silter, M., Kögler, H., Kleinschmidt, M., Wilting, J., Schäfer, K., Maier, L.S., Katschinski D.M.: Impaired cardiac function in Hif-1a+/- mice as a consequence of chronic pressure overload. Pflug. Arch. Eu. J. Phy. 459: 569-577 (2010)

Becker J., Pavlakovic H., Ludewig F., Wilting F., Weich, H., Albuquerque R., Ambati J., Wilting J.: Neuroblastoma progression correlates with down-regulation of the lymphangiogenesis inhibitor sVEGFR2. Clin. Cancer Res. 16: 1431-1441 (2010)

Schniedermann, J., Rennecke, M., Buttler, K., Richter, G., Städtler, A.M., Norgall, S., Badar, M., Barleon, B., May, T., Wilting, J., Weich, H.A.: Mouse lung microvascular endothelial progenitor cells exhibit a high capacity for the formation of blood and lymphatic vessels. BMC Cell Biol. 11: 50 (2010)

Wang, B., Pu, Q., De, R., Patel, K., Christ, B., Wilting, J., Huang, R.: Commitment of chondrogenic precursors of the avian scapula takes place after epithelio-mesenchymal transition of the dermomyotome. BMC Dev. Biol. 10: 91 (2010)

Becker J., Wang B., Pavlakovic H., Buttler K., Wilting J.: Homeobox transcription factor Prox1 in sympathetic ganglia of vertebrate embryos: correlation with human stage 4s neuroblastoma. Ped. Res. 68: 112-117 (2010)

von Kaisenberg CS, Wilting J, Dörk T, Nicolaides KH, Meinhold-Heerlein I, Hillemanns P, Brand-Saberi B (2010) Lymphatic capillary hypoplasia in the skin of fetuses with increased nuchal translucency and Turner's syndrome: comparison with trisomies and controls. Mol Hum Reprod 16: 778-789 (2010)

Buttler, K., Schniedermann, J., Weich, H.A., Wilting, J.: Isolierung bipotenter endothelialer Vorläuferzellen aus der Lunge adulter Mäuse. Lymphologie in Forschung und Praxis 14: 58-64 (2010)

Wilting, J.: Frühentwicklung. In: Anatomie. (eds. Zilles, K., Tillmann, B.) Springer Verlag, Berlin, Heidelberg (2010) pp 51 - 74

Pavlakovic, H., Becker, J., Albuquerque, R., Wilting, J., Ambati, J.: Soluble VEGFR-2: an anti-lymphangiogenic variant of VEGF receptors. Ann. NY Acad. Sci. 1207 S1: E7-E15 (2010)

Wilting, J., Albuquerque, R., Ambati, J.: Endogenous anti-lymphangiogenesis. Lymphology 43 (Suppl.): 30 – 36 (2010)

2009

Albuquerque, R., Hayashi, T., Cho, W.G., Kleinman, M.E., Takeda, A., Baffi, J.Z., Yamada, K., Kaneko, H., Rich, M.G., Chappell, J., Wilting, J., Weich, H.A., Yamagami, S., Amano, S., Mizuki, N., Alexander, J.S., Peterson, M.L., Brekken, R.A., Hirashima, M., Capoor, S., Usui, T., Ambati, B.K., Ambati, J.: Alternatively spliced VEGF receptor-2 is an essential endogenous lymphangiogenesis inhibitor. Nat. Med. 15: 1023-1030 (2009)

Volland, S., Kugler, W., Schweigerer, L., Wilting, J., Becker, J. Stanniocalcin 2 promotes invasion and is associated with metastatic stages in neuroblastoma. Int. J. Cancer 125: 2049-2057 (2009)

Buttler, K., Kasten, P., Wilting, J.: Molekulare Charakteristika des Lymphangioms beim Säugling. Lymphologie in Forschung und Praxis 13: 22-26 (2009)

Baumeister, R., Berens v. Rautenfels, D., Brauer, W.J., Döller, W., Felmerer, G., Földi, E., Koller, M., Flaggl, F., Oberlin, M., Schacht, V., Tiedjen, K.-U., Ure, Ch., Wilting, J. (2009) Diagnostik und Therapie der Lymphödeme. Leitlinie der Gesellschaft Deutschsprachiger Lymphologen. AWMF online; http://www.leitlinien.net/

The diagnosis and treatment of peripheral lymphedema. 2009 consensus document of the International Society of Lymphology. Lymphology 42: 51-60 (2009)

Wilting, J., Becker, J., Buttler, K., Weich, H.A.: Lymphatics and inflammation. Curr. Med. Chem. 16: 4581-4592 (2009)

2008

Becker, J., Volland, S., Noskova, I., Schramm, A., Schweigerer, L., Wilting, J.: Keratoepithelin reverts the suppression of tissue factor pathway inhibitor 2 (TFPI2) by MYCN in human neuroblastoma: a mechanism to inhibit invasion. Int. J. Oncol. 32: 235-240 (2008)

Dudas, J., Mansuroglu, T., Moriconi, F., Haller, F., Wilting, J., Lorf, T., Fuzesi, L., Ramadori, G.: Altered regulation of Prox1-gene-expression in liver tumors. BMC Cancer 8: 92 (2008)

Buttler, K., Ezaki, T., Wilting, J.: Proliferating mesodermal cells in murine embryos exhibiting macrophage and lymphendothelial characteristics BMC Dev. Biol. 8: 43 (2008)

Rutscher, K., Wilting, J.: Transcription factor FoxC2 demarcates the jugular, lymphangiogenic region in avian embryos. Lymphology 41: 18-28 (2008)

2007

Norgall S., Papoutsi M., Rössler J., Schweigerer, L., Wilting J., Weich HA.: Elevated expression of VEGFR-3 in lymphatic endothelial cells from lymphangiomas. BMC Cancer 7: 105 (2007)

Wilting, J., Buttler, K., Schulte, I., Papoutsi, M., Schweigerer, L., Männer J.: The proepicardium delivers hemangioblasts but not lymphangioblasts to the developing heart. Dev. Biol. 305: 451-459 (2007)

Ebenebe, C.U., Diehl, S., Bartnick, K., Dörge, H., Becker, J., Schweigerer, L., Wilting, J.: Three reactive compartments in venous malformations. Thromb. Haemost. 97: 763-773 (2007)

Valasek, P., Macharia, R., Neuhuber, W.L., Wilting, J., Becker, D.L., Patel, K.: Lymph heart in chick - somitic origin, development and embryonic oedema. Development 134: 4427-4436 (2007)

Papoutsi, M, Dudas, J., Becker, J., Opitz, L., Tripodi, M., Ramadori, G., Wilting, J.: Gene regulation by the homeobox transcription factor Prox1 in murine hepatoblasts. Cell Tissue Res. 330: 209-220 (2007)

Kasten, P., Schnöink G., Bergmann A., Papoutsi M., Buttler K., Rössler J, Weich HA., Wilting J.: Similarities and differences of human and experimental mouse lymphangiomas. Dev. Dynam. 236: 2952-2961 (2007)

Wilting, J., Papoutsi, M., Buttler, K., Becker, J.: Embryonic development of the lymphovascular system and tumor lymphangiogenesis. Cancer Treat. Res. 135:17-24 (2007)

Becker, J., Ebenebe, C.U., Diehl, S., Bartnick, K., Schweigerer, L., Wilting, J.: Deregulated gene expression gives rise to inflammation and arterialization of endothelial cells in congenital venous malformation. Lymphology 40(suppl): 215-220 (2007)

Papoutsi, M., Hecht, M., Schweigerer, L., Wilting, J.: The avian chorioallantoic membrane as a tool to monitor tumor lymphangiogenesis and invasiveness. Lymphology 40 (Suppl.): 66-70 (2007)

Wilting, J., Buttler, K., Rössler, R., Norgall, S., Schweigerer, L., Weich, H.A., Papoutsi, M.: Embryonic development and malformation of lymphatic vessels. In: Novartis Foundation Symposium No. 283 “Vascular Development”. John Wiley, Chichester, 2007, pp 220-229

Wilting, J., Papoutsi, M., Buttler, K., Becker, J.: Embryonic development of the lymphvascular system and tumor lymphangiogenesis. In: Cancer metastasis and the lymphovascular system. (ed. Leong SPL), Springer, New York, NY, 2007, pp 17-24

2006

Schneider, M., Büchler, P., Giese, N., Wilting, J., Büchler, M.W., Friess, H.: Role of lymphangiogenesis and lymphangiogenic factors during pancreatic cancer progression and lymphatic spread. Int. J. Oncol. 28: 883-890 (2006)

Wilting, J., Aref, Y., Huang, R., Tomarev, S.I., Schweigerer, L., Christ, B., Valasek, P., Papoutsi, M.: Dual origin of avian lymphatics. Dev. Biol. 292: 165-173 (2006)

Buttler, K., Kreysing, A., von Kaisenberg, C.S., Schweigerer, L., Gale, N., Papoutsi, M., Wilting, J.: Mesenchymal cells with leukocyte and lymphendothelial characteristics in murine embryos. Dev. Dyn. 235: 1554-1562 (2006)

Dudas, J., Mansuroglu, T., Batusic, D., Elmaouhoub, A., Cimica, V., Papoutsi, M., Tron, K., Saile, B., Pieler, T., Wilting, J., Ramadori, G.: Prospero-related homeobox 1 (Prox1) is a stable hepatocyte marker during liver development, injury and regeneration, and is absent from "oval cells". Histochem. Cell Biol. 126: 549-562 (2006)

Witte MH, Jones K, Wilting J, Dictor M, Selg M, McHale N, Gershenwald JE, Jackson D. Structure-function relationships in the lymphatic system and implications for cancer biology. Cancer Metastasis Rev. 25: 159-184 (2006)

Wilting, J., Becker, J.: Two endothelial cell lines derived from the somite. Anat. Embryol. 211 Suppl 7: 57-63 (2006)

Becker, J., Wilting, J., Schweigerer, L.: Tumour angiogenesis. In: Apoptosis and cancer therapy. (eds. Fulda, S., Debatin, K.-M.) Wiley-VCH Verlag, Weinheim, Germany 2006, pp 421-440

2005

Diehl, S., Bruno R., Wilkinson, G.A., Loose, D.A., Wilting, J., Schweigerer, L., Klein, R.: Altered expression patterns of ephrinB2 and EphB2 in human umbilical vessels and congenital venous malformations. Ped. Res. 57, 537-544 (2005)

Schramm, A., v. Schuetz, V., Christiansen, H., Havers, W., Papoutsi, M., Wilting, J., Schweigerer, L.: High activin A-expression in human neuroblastoma: suppression of malignant potential and correlation with favorable clinical outcome. Oncogene 24: 680-687 (2005)

Hecht, M., Schulte J., Eggert, A., Wilting, J., Schweigerer, L.: The neurotrophin receptor TrkB cooperates with c-Met in enhancing neuroblastoma invasiveness. Carcinogenesis 26: 2105-2115 (2005)

Wilting, J., Hawighorst, T., Hecht, M., Christ. B., Papoutsi, M.: Development of lymphatic vessels: Tumour lymphangiogenesis and lymphatic invasion. Curr. Med. Chem. 12: 3043-3053 (2005)

2004

Hagedorn, M.A., Balke, M., Schmidt, A., Bloch, W., Kurz, H., Javerzat, S., Rousseau, B., Wilting, J., Bikfalvi, A.: VEGF coordinates interaction of pericytes and endothelial cells during vasculogenesis and experimental angiogenesis Dev. Dyn. 230: 23-33 (2004)

Dudas, J., Papoutsi, M., Hecht, M., Elmaouhoub, A., Saile, B., Christ, B., Tomarev, S.I., von Kaisenberg, C.S., Schweigerer, L., Ramadori, G., Wilting, J.: The homeobox transcription factor Prox1 is highly conserved in embryonic, adult and transformed hepatocytes, but is absent from bile duct epithelium. Anat. Embryol. 208: 359-366 (2004)

Hecht, M., Tran, H., Papoutsi, M., Wilting, J., Schweigerer, L.: HGF / c-Met signaling promotes the progression of experimental human neuroblastomas. Cancer Res. 64: 6109-6118 (2004)

Nimmagadda, S., Loganathan, P.G., Wilting, J., Christ, B., Huang, R.: Expression pattern of VEGFR-2 (Quek1) during quail development. Anat. Embryol. 208: 219-224 (2004)

Wilting, J., Schweigerer, L.: Development and engineering of lymphatic endothelial cells: clinical implications. Curr. Pharm. Design 10: 75-80 (2004)

Wilting, J., Papoutsi, M., Becker, J.: The lymphatic vascular system: secondary or primary? Lymphology 37: 98-106 (2004)

Wilting, J., Schweigerer, L.: Development and engineering of lymphatic endothelial cells: clinical implications. Phlebol. Digest 17: 18-20 (2004) Kommentiert in: Damstra R,J.: Phlebol. Digest 17: 20 (2004)

Hagedorn, M., Wilting, J.: Chick chorioallantoic membrane assay: growth factor and tumor-induced angiogenesis and lymphangiogenesis. In: Methods in endothelial cell biology. (ed. Augustin H.) Springer Verlag, Berlin, Heidelberg, 2004, pp 247-261

Wilting, J., Schweigerer, L.: Engineering of lymphatic endothelial cells. Phlebol. Digest 17: 18-20 (2004)

Diehl, S., Papoutsi, M., Rössler, J., Schweigerer, L., Wilting, J.: Heterogeneity of tumour vasculature. Lymphology 37 (Suppl.): 49-56 (2004)

2003

Wilting, J., Tomarev S.I., Christ, B., Schweigerer L.: Lymphangioblasts in embryonic lymphangiogenesis. Lymphat. Res. Biol. 1: 33-40 (2003)

Krishnan, J., Kirkin, V., Steffen, A., Hegen, M., Weih, D., Tomarev, S., Wilting, J., Sleeman., J.: Differential in vivo and in vitro expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in tumors and its relationship to lymphatic metastasis in immunocompetent rats. Cancer Res. 63: 713-722 (2003)

He, L., Papoutsi, M., Huang, R., Tomarev, S.I., Christ, B., Kurz, H., Wilting. J.: Three different fates of cells migrating from somites into the limb bud. Anat. Embryol. 207: 29-34 (2003)

Pröls, F., Heidgress, D., Wilting, J., Frank, G., Christ, B.: Three dimensional tissue culture as experimental model for the evaluation of angiogenic factors. German Journal of Obstetrics and Gynecology 63: 1256-1261 (2003)

Wilting, J., Christ B., Yuan, L., Eichmann A.: Cellular and molecular mechanisms of embryonic hemangiogenesis and lymphangiogenesis. Naturwissenschaften 90: 433-448 (2003)

Jeltsch, M., Tammela, T., Alitalo, K., Wilting, J.: Genesis and pathogenesis of lymphatic vessels. Cell Tissue Res. 314: 69-84 (2003)

2002

Kündgen, L.R., Thoma, C., Köck, J., Wilting, J., Koch, H.K., Blum, H.E., Offensperger, W.B., von Weizsäcker, F.: Inhibition of duck hepatitis B virus replication by intrahepatic expression of an antiviral resistance gene. J. Mol. Med. 80: 187-195 (2002)

Kurz, H., Lauer, D., Papoutsi, M., Christ, B., Wilting, J.: Pericytes in experimental MDA-MB231 tumor angiogenesis. Histochem. Cell Biol. 117: 527-534 (2002)

Papoutsi, M., Othman-Hassan, K., Christ, B., Patel, K., Wilting, J.: Development of an arterial tree in C6 gliomas but not in A375 melanomas. Histochem. Cell Biol. 118: 241-249 (2002)

Wilting, J., Papoutsi, M., Christ, B., Nicolaides, K.H., von Kaisenberg, C.S., Borges, J., Stark, G.B., Alitalo, K., Tomarev, S.I., Niemeyer, C., Rössler, J.: The transcription factor Prox1 is a marker for lymphatic endothelial cells in normal and diseased tissues. FASEB J. 16: 1271-1273 (2002) (online: Express Article 10.1096/fj.01-1010fje)

Olszewski, W., Lammie, P., Gashev, A., Padera, T., Rosen, E., Mouta, C., Oliver, G., Simonian, S., Gashev, A., Miller, A., Gannon, B., Wilting, J.: Aspects of lymphatic biology and disease - panel discussion. Lymphatic continuum: lymphatic biology and disease. Ann. N.Y. Acad. Sci. 979: 188-196 (2002)

Rockson, S.G., Niklason, L., Zawieja, D., Ochoa, E., Granger, C., Gannon, B., Wilting, J., Simonian, S., Olszewski, W., Hayward, N.: New tools for lymphatic investigation - panel discussion. Lymphatic continuum: lymphatic biology and disease. Ann. N.Y. Acad. Sci. 979: 35-38 (2002)

Hagedorn, M., Zilberberg, L., Wilting, J., Canron, X., Carrabba, C., Pluderi, M., Bello, L., Bikfalfi, A.: Domain swapping in a C-terminal fragment of platelet factor 4 generates potent angiogenesis inhibitors. Cancer Res. 62: 6884-6890 (2002)

Wilting, J.: Integrated anatomy of the vascular system. In: Panvascular Medicine (eds. Lanzer, P., Topol, E.J.) Springer Verlag, Heidelberg, New York (2002) pp 50 – 75
Kommentiert in: New Engl. J. Med. 349: 1 (2003) by R.E. Zierler, Washington

Wilting, J.: Das humane Gefäßsystem: Von der Embryologie zur Klinik. In: Benigne Gefäßfehl- und neubildungen. (eds. Landthaler, Hohenleutner, Vogt) Blackwell Verlag, Berlin, Wien (2002) pp 1-14

2001

Huang, R., Zhi, Q., Patel K., Wilting, J., Christ, B.: Dual origin and segmental organisation of the avian scapula. Development 127: 3789-3794 (2000)

Sudo, H., Tonegawa, A., Yoshiko, A., Aoyama, H., Mizutani-Koseki Y., Moriya, H., Wilting. J., Christ, B., Koseki, H.: Inductive signals from the somatopleure mediated by bone morphogenetic proteins are essential for the formation of the sternal component of avian ribs. Dev. Biol. 232: 284-300 (2001)

Papoutsi, M., Sleeman, J., Wilting, J.: Interaction of rat tumor cells with blood vessels and lymphatics of the avian chorioallantoic membrane. Microsc. Res. Tech. 55: 100-107 (2001)

Wilting, J.: New perspectives in lymphangiogenesis research. Microsc. Res. Tech. 55: 59-60 (2001)

Papoutsi, M., Tomarev S.I., Eichmann A., Pröls F., Christ, B., Wilting, J.: Endogenous origin of the lymphatics in the avian chorioallantoic membrane. Dev. Dyn. 222: 238-251 (2001)

Othman-Hassan, K., Patel, K., Papoutsi, M., Rodriguez-Niedenfür, M., Christ, B., Wilting, J.: Arterial identity of endothelial cells is controlled by local cues. Dev. Biol. 237: 398-409 (2001)

Pröls, F., Mayer, M.P., Renner, O., Czarnecki, P., Ast, M., Gässler, C., Wilting, J., Kurz, H., Christ, B.: Upregulation of the Co-chaperone Mdg1 during in vitro angiogenesis. Exp. Cell Res. 269: 42-53 (2001)

Hautmann, M., Wilting, J., Haller, H., Leutz, A.: Adenovirus-mediated gene transfer as a tool to study angiogenesis in the chick embryo. Dev. Genes Evol. 211: 611-616 (2001)

Rodriguez-Niedenführ, M., Papoutsi, M., Christ, B., Nicolaides, K.H., von Kaisenberg, C.S., Tomarev S.I., Wilting J.: Prox1 is a marker of ectodermal placodes, endodermal compartments, lymphatic endothelium and lymphangioblasts. Anat. Embryol. 204: 399-406 (2001)

Wilting, J., Papoutsi, M., Othman-Hassan, K., Rodriguez-Niedenführ, M., Pröls, F., Tomarev, S.I., Eichmann, A.: Development of the avian lymphatic system. Microsc. Res. Tech. 55: 81-91 (2001)

Papoutsi, M., Christ, B., Wilting, J.: Studies on lymphangiogenesis in avian embryos. In: Teratologie (ed. Fanghähnel, J.) Tectum Verlag, Marburg, 2001, pp 139-148

2000

Huang, R., Zhi, Q., Schmidt, C., Wilting, J., Brand-Saberi, B., Christ, B. Sclerotomal origin of the ribs. Development 127: 527-532 (2000)

Wilting, J., Schneider, M., Papoutsi, M., Alitalo, K., Christ, B. An avian model in studies of embryonic lymphangiogenesis. Lymphology 33: 81-94 (2000)

Wilting, J., Papoutsi, M., Schneider, M., Christ, B. The lymphatic endothelium of the avian wing is of somitic origin. Dev. Dynam. 217: 271-278 (2000)

Papoutsi, M., Kurz, H., Schächtele, C., Marmé, D., Christ, B., Wilting, J.: Induction of the blood-brain barrier marker neurothelin/HT7 in endothelial cells by a variety of tumors in chick embryos. Histochem. Cell Biol. 113: 105-113 (2000)

Breit, S., Asham, K., Wilting, J., Rössler, J., Fotsis, T., Schweigerer, L.: The N-myc oncogene in human neuroblastoma cells: down-regulation of an angiogenesis inhibitor identified as activin A. Cancer Res. 60: 4596-4601 (2000)

Papoutsi, M., Siemeister, G., Weindel, K., Tomarev, S., Kurz, H., Schächtele, C., Martiny-Baron, G., Christ, B., Marmé, D., Wilting, J.: Active interaction of human A375 melanoma cells with the lymphatics in vivo. Histochem. Cell Biol. 114: 373-385 (2000)

Huang, R., Zhi, Q., Patel K., Wilting, J., Christ, B.: Contribution of single somites to the skeleton and the muscles of the occipital and cervical regions in avian embryos. Anat. Embryol. 202: 375-383 (2000)

Wilting, J., Christ B.: Development of the limb bud vascular system. In: Morphogenesis of the endothelium. (eds. W. Risau, G. Rubanyi) Harwood Academic Publishers, London, pp. 189-206 (2000)

Christ, B., Huang, R., Wilting, J.: The development of the avian vertebral column. Anat. Embryol. 202: 179-194 (2000)

1999

Schneider, M., Othman-Hassan, K., Christ, B., Wilting, J.: Lymphangioblast in the developing avian wing bud. Dev. Dynam. 216: 311-319 (1999)

Wilting, J., Neeff, H., Christ, B.: Embryonic lymphangiogenesis. Cell Tissue Res. 297: 1-13 (1999)

1998

Oh S.-J, Kurz H., Christ B., Wilting J.: Platelet-derived growth factor-B induces transformation of fibrocytes into spindle-shaped myofibroblasts in vivo. Histochem. Cell Biol. 109: 349-357 (1998)

Kurz, H., Wilting, J., Sandau, K., Christ, B.: Automated evaluation of angiogenic effects mediated by VEGF and PlGF homo- and heterodimers. Microvas. Res. 55: 92-102 (1998)

Aitkenhead, M., Christ, B., Eichmann, E., Wilson, D.J., Wilting, J.: Paracrine and autocrine regulation of vascular endothelial growth factor during tissue differentiation in the quail. Dev. Dynam. 212: 1-13 (1998)

Prepens, U., Barth, H., Wilting, J., Aktories K.: Effects of Clostridium botulinum C2 toxin on Fc,RI-mediated secretion and tyrosine phosphorylation in RBL cells. Naunyn-Schmiedeberg`s Arch. Pharmacol. 357: 323-330 (1998)

Feucht, M., Christ, B., Wilting, J.: Vascular Endothelial Growth Factor induziert kardiovaskuläre Fehlbildungen in der Embryonalentwicklung. Ann. Anat. 180: 387-389 (1998)

Christ, B., Schmidt, C., Huang, R., Wilting, J., Brand-Saberi, B.: Segmentation of the vertebrate body. Anat. Embryol. 197: 1-8 (1998)

Kurz, H., Sandau, K., Wilting, J., Christ, B.: Blood vessel growth: analysis and computersimulation, fractality and optimality. In: Vascular morphogenesis: in vivo, in vitro and in mente. (eds. Little, C., Mironov, V., Sage, H.) Birkhäuser, Boston, 1998, pp 189-203

1997

Wilting, J., Eichmann, A., Christ, B.: Expression of the avian VEGF receptor homologues Quek1 and Quek2 in blood-vascular and lymphatic endothelial and non-endothelial cells during quail embryonic development. Cell Tissue Res. 288: 207-223 (1997)

Oh S.-J., Jeltsch M.M., Birkenhäger, R., McCarthy, J.E.G., Weich, H.A., Christ, B., Alitalo K., Wilting,J.: VEGF and VEGF-C: specific induction of angiogenesis and lymphangiogen
esis in the differentiated avian chorioallantoic membrane. Dev. Biol. 188: 96-109 (1997)

Feucht, M., Christ, B., Wilting, J.: VEGF induces cardiovascular malformation and embryonic lethality. Am. J. Pathol. 151: 1407-1416 (1997) Kommentiert in: Auerbach, R., Auerbach, W. Profound effects on vascular development caused by perturbations during organogenesis. Am. J. Pathol. 151: 1183- 1186 (1997)

Wilting, J., Kurz, H.: VEGF-C, ein lymphangiogener Wachstumsfaktor. LymphForsch. 2: 68-71 (1997)

Wilting, J.: Development and differentiation of blood vessels in the central nervous system. In: Neuroendocrinology: retrospect and perspectives (eds. Korf, H.-W., Usadel, K.H.) Springer, Heidelberg 1997, pp 305-312

1996

Wallin, J., Eibel, H., Neubüser, A., Wilting, J., Koseki, H., Balling, R.: Pax-1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation. Development 122: 23-30 (1996)

Grothe, C., Brand-Saberi, B., Wilting, J., Christ, B.: Fibroblast growth factor receptor 1 in skeletal and heart muscle cells: Expression during early avian development and regulation after notochord transplantation. Dev. Dyn. 206: 310-317 (1996)

Müller, T.S., Ebensperger, C., Neubüser, A., Koseki, H., Balling, R., Christ, B., Wilting, J.: Expression of avian Pax-1 and Pax-9 is intrinsically regulated in the pharyngeal endoderm, but depends on environmental influences in the paraxial mesoderm. Dev. Biol. 178: 403-417 (1996)

Huang, R., Zhi, Q., Neubüser, A., Müller, T.S., Brand-Saberi, B., Christ, B., Wilting, J.: Function of somite and somitocoele cells in the formation of the vertebral motion segment in avian embryos. Acta Anat. 155: 231-241 (1996)

Wilting, J., Birkenhäger, R., Eichmann, A., Kurz, H., Martiny-Baron, G., Marmé, D., McCarthy, J.E., Christ, B., Weich, H.A.: VEGF121 induces proliferation of vascular endothelial cells and expression of flk-1 without affecting lymphatic vessels of the chorioallantoic membrane. Dev. Biol. 176: 76-85 (1996)

Brand-Saberi, B., Gamel, A.J., Krenn, V., Müller, T.S., Wilting, J. Christ B.: N-cadherin is involved in myoblast migration and muscle differentiation in the avian limb bud. Dev. Biol. 178: 160-173 (1996)

Birkenhäger, R., Schneppe, B., Röckl, W., Wilting, J., Weich, H.A., McCarthy, J.E.G.: Synthesis and physiological activity of heterodimers comprising different splice-forms of vascular endothelial growth factor and placenta growth factor. Biochem. J. 326: 703-707 (1996)

Brand-Saberi, B., Müller, T.S., Wilting, J., Christ, B., Birchmeier, C.: Scatter factor/hepatocyte growth factor (SF/HGF) induces emigration of myogenic cells at interlimb level in vivo. Dev. Biol. 179: 303-308 (1996)

Christ, B., Huang, R., Zhi Q., Wilting, J.: Die Entwicklung des vertebralen Bewegungssegments. Manuelle Medizin 34: 178-182 (1996)

Wilting, J., Christ, B.: Embryonic angiogenesis. A review. Naturwissenschaften 83: 153-164 (1996)

Wilting, J.: Die Entwicklung der Wirbelsäule und des zerviko-okzipitalen Übergangs. In: Die kindliche Wirbelsäule. (eds. R. Stücker, A. Reichelt) Sympomed Verlag, München 1996, pp 1-9

Wilting, J., Müller, T.S., Ebensperger, C., Brand-Saberi, B., Christ, B., Neubüser, A., Balling, R., Koseki, H.: Development of the vertebral column: Morphogenesis and genes. In: Aspects of Teratology. Vol. 1 (eds. R. Vogel, J. Fanghänel, J. Giebel) Tectum Verlag, Marburg 1996, pp 73-80

1995

Wilting, J., Brand-Saberi, B., Huang, R., Zhi, Q., Köntges, G., Ordahl,CP., Christ, B.: Angiogenic potential of the avian somite. Dev. Dynam. 202: 165-171 (1995)

Brand-Saberi, B., Seifert, R., Grim, M., Wilting, J., Kühlewein M., Christ, B: Blood vessel formation in the avian limb bud involves angioblastic and angiotrophic growth. Dev. Dynam. 202: 181-194 (1995)

Kurz, H., Ambrosy, S., Wilting, J., Marmé, D., Christ, B.: The proliferation pattern of capillary endothelial cells in chorioallantoic membrane development indicates local growth control, which is counteracted by vascular endothelial growth factor application. Dev. Dynam. 203: 174-186 (1995)

Ebensperger, C., Wilting, J., Brand-Saberi, B., Mizutani Y., Christ B., Balling R., Koseki H.: Pax-1, a regulator of sclerotome development is induced by notochord and floor plate signals in avian embryos. Anat. Embryol. 191: 297-310 (1995)

Wilting, J., Ebensperger, C., Müller, T.S., Koseki, H., Wallin, J., Christ, B.: Pax-1 in the development of the cervico-occipital transitional zone. Anat. Embryol. 192: 221-227 (1995)

Simon, J.C, Dittmar H.C., de Roche, R., Wilting, J., Christ, B., Schöpf, E.: Rapid purification of human Langerhans cells using paramagnetic microbeads. Exp. Dermatol. 4: 155-161 (1995)

Wilting, J., Brand-Saberi, B., Kurz, H., Christ, B.: Development of the embryonic vascular system. Cell. Mol. Biol. Res. 41: 219-232 (1995)

Christ, B., Wilting, J.: Development of the vertebral column and the cervico-occipital transitional zone: Morphogenesis and genes. In: De oude wervelkolom. (eds. S.A. Duursma, J.A. Raymakers, P.A.F. Jansen) Academisch Ziekenhuis Utrecht 1995, pp 5-12

1994

Fundele, R., Bober, E., Arnold, H.H., Grim, M., Bender, R., Wilting, J., Christ, B.: Early skeletal muscle development proceeds normally in parthenogenetic mouse embryos. Dev. Biol. 161:30-36 (1994)

Wallin, J., Wilting, J., Koseki, H., Fritsch, R., Christ, B., Balling, R.: The role of Pax-1 in axial skeleton development. Development 120:1109-1121 (1994).

Huang, R., Zhi, Q., Wilting, J., Christ, B.: The fate of somitocoele cells in avian embryos. Anat. Embryol. 190: 243-250 (1994)

Bober, E., Brand-Saberi, B., Ebensperger, C., Wilting, J., Balling, R., Paterson, B.M., Arnold, H.-H., Christ, B.: Initial steps of myogenesis in somites are independent of influence from axial strucures. Development 120: 3073-3082 (1994)

Wilting, J., Kurz, H., Brand-Saberi, B., Steding, G., Yang, Y.X., Hasselhorn, H.-M., Epperlein, H.-H., Christ, B.: Kinetics and differentiation of somite cells forming the vertebral column: studies on human and chick embryos. Anat. Embryol. 190: 573-581 (1994)

Balling, R., Koseki, H., Wallin, J., Ebensperger, C., Wilting, J., Christ, B.: Mouse genetics and the development of the vertebral column. Proc. Greenwood Genetics Center 13: 58-60 (1994)

Dittmar, H.C., Wilting, J., deRoche, H., Christ, B., Schöpf, E., Simon, J.C.: A rapid new method to purify human Langerhans Cells (LC) using paramagnetic beads. J. Invest. Dermatol. 102: 582-582 (1994)

1993

Fiebich, B.L., Jäger, B., Schöllmann, C., Weindel, K., Wilting, J., Kochs, G., Marmé, D., Hug, H., Weich, H.A.: Synthesis and assembly of functionally active human vascular endothelial growth factor homodimers in insect cells. Eur. J. Biochem. 211:19-26 (1993)

Wilting, J., Weich, H.A., Christ, B.: Effects of vascular endothelial growth factor and basic fibroblast growth factor: Application with corneal grafts on the chorioallantoic membrane. Acta Anat. 147:207-215 (1993)

Wilting, J., Christ, B., Bokeloh, M., Weich, H.A.: In vivo effects of vascular endothelial growth
factor on the chicken chorioallantoic membrane. Cell Tissue Res. 274:163-172 (1993)

Brand-Saberi, B., Ebensperger, C., Wilting, J., Balling, R., Christ, B.: The ventralizing effect of the notochord on somite differentiation in chick embryos. Anat. Embryol. 188:239-245 (1993)

Koseki, H., Wallin, J., Wilting, J., Mizutani, Y., Kispert, A., Ebensperger, C., Herrmann, B.G., Christ, B., Balling R.: A role for Pax-1 as a mediator of notochordal signals during the dorsoventral specification of vertebrae. Development 119:649-660 (1993)

Christ, B., Brand-Saberi, B., Wilting, J.: Entwicklungsbiologische Grundlagen der Teratogenese. In: Teratologie. (eds. Korte R., Fanghänel J., Gossrau R.), de Gruyter, Berlin, New York 1-15 (1993)

Wilting, J., Christ, B.: Kontrollmechanismen der embryonalen Blutgefäßbildung. In: Teratologie. (eds. Korte R., Fanghänel J., Gossrau R.), de Gruyter, Berlin, New York 27-34 (1993)

Kurz, H., Wilting, J., Christ, B.: Multivariate characterization of blood vessel morphogenesis in the avian chorioallantoic membrane (CAM): cell proliferation, length density and fractal dimension. In: Fractals in biology and medicine (eds. Lossa GA, Nonnenmacher TF., Weibel ER.) Birkhäuser, Basel 1993, pp 132-140

1992

Wilting, J., Christ, B.: A morphological study of the rabbit corneal assay. Ann. Anat. 174:549-556 (1992)

Wilting, J., Christ, B., Weich, H.A.: The effects of growth factors on the day 13 chorioallantoic-membrane (CAM): A study of VEGF165 and PDGF-BB. Anat. Embryol. 186:251-257 (1992)

Christ, B., Brand-Saberi, B., Grim, M., Wilting, J.: Local signalling in dermomyotomal cell type specification. Anat. Embryol. 186:505-510 (1992)

Christ, B., Wilting, J.: From somites to vertebral column. Ann.Anat. 174:23-32 (1992)

Christ, B., Wilting, J.: Die Entwicklung der Halswirbelsäule unter besonderer Berücksichtigung des kranio-cervikalen Überganges. 10. Offene Frankfurter Schmerzkon¬ferenz. (Herausgeber C. Thomalski, E. Schmitt, M. Gross) Fischer, Stuttgart (1992), pp. 37-48

Wilting, J., Christ, B., Grim, M., Wilms, P.: Angiogenic capacity of early avian mesoderm. In: Formation and differentiation of early embryonic mesoderm (eds. J.W. Lash, R. Bellairs) NATO ASI Series Plenum Press, New York, London 1992, 315-322

1991

Wilms, P., Christ, B., Wilting, J., Wachtler, F.: Distribution and migration of angiogenic cells from grafted avascular intraembryonic mesoderm. Anat. Embryol. 183: 371-377 (1991)

Wilting, J., Christ, B., Bokeloh, M.: A modified chorioallantoic membrane (CAM) assay for qualitative and quantitative study of growth factors. Studies on the effects of carriers, PBS, angiogenin and bFGF. Anat. Embryol. 183:259-271 (1991)

Christ, B., Epperlein, H.-H., Flöel, H., Wilting, J.: The somite-muscle relationship in the avian embryo. Developmental patterning of the vertebrate limb (eds. Hinchliffe et al.) pp. 265-271, Plenum Press, New York (1991)

Poelmann, R.E., Christ, B., Jacob, M., Mentink, M.M.T., Wilting, J.: Zell-Matrix-Dialoge induzieren die Mesektodermbildung. Verh. Anat. Ges. 84:47-48 (1991)

Wilting, J., Bokeloh, M., Christ, B.: Basic Fibroblast Growth Factor (bFGF) und PBS im CAM-Assay. Verh. Anat. Ges. 85:543-545 (1991)

1990

Wilting, J., Christ, B.: Untersuchungen der Entwicklung des Plexus choroideus und der Epiplexuszellen bei Vogelchimären. Verh. Anat. Ges. 83:197-199 (1990)

1989

Wilting, J., Christ, B.: An experimental and ultrastructural study on the development of the avian choroid plexus. Cell Tissue Res. 255:487-494 (1989)

1988

Wilting, J.: Ultrastrukturelle und funktionellle Untersuchungen der Entwicklung des Plexus choroideus bei Vogelchimären. Dissertation, Bochum 1988

1987

Wilting, J., Christ, B.: Untersuchungen zur Entwicklung des Plexus choroideus bei Vogelembryonen. Verh. Anat. Ges. 81:543-545 (1987)